Manchester United will look to preserve their nine-match winning streak in all competitions when they host fierce rivals Liverpool in the Premier League.
Arsenal trio Olivier Giroud, Laurent Koscielny and Francis Coquelin have all signed fresh contracts at the Emirates.
German international Mesut Ozil has insisted that he is happy to commit his future to Arsenal once they club resolve the contract situation of manager Arsene Wenger.
Chelsea boss Antonio Conte is expected to make multiple changes as his side take on League One outfit Peterborough in the third round of the FA Cup.
Premier League leaders Chelsea will look to extend their five-point gap over Liverpool when they take on London rivals Tottenham Hotspur at White Hart Lane.