Summer signing Henrikh Mkhitaryan has overcome a thigh injury suffered on international duty and he is set to return for the clash against Zorya Luhansk in the Europa League.
James Rodriguez is currently in Colombia obtaining a UK work permit ahead of his proposed move to the Premier League.
Manchester United go into the game against Sunderland on Boxing Day with a three-match winning streak in the top flight.
Manchester United will seek to avenge their 4-0 league defeat at the hands of Chelsea earlier in the season when they take on the Blues in the quarter-final of the FA Cup.
Bayer Leverkusen ace Hakan Calhanoglu would take the chance of joining Manchester United, should an opportunity arise in the future. The midfielder is also a transfer target for Chelsea.